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Hedrin’s efficacy is a result of its active ingredients, Dimeticone (contained in Hedrin 4% Lotion and Hedrin Once) and Activdiol (contained in Hedrin Treat & Go and Protect & Go). All formulations are patented and have been shown to be effective at killing head lice in clinical trials and even work on lice that have developed a resistance to traditional pesticide treatments.
Head lice have a unique strategy of water management. Instead of producing urine they eliminate excess water via tiny passages in their exoskeleton called spiracles. The active ingredient Dimeticone, a silicone oil, disrupts this process of water management by coating the lice, causing them to become permanently immobile, and blocking the spiracles preventing them from getting rid of excess water. As a result, any lice that have recently fed suffer from death by gut rupture and, the ones that haven’t, die of starvation.
Dimeticone and penetrol.
Hedrin Once Spray Gel may be unsuitable for certain people. Do not use this product if you are allergic to any of the ingredients.
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